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A study is being conducted for individuals with the autoimmune disease polymyositis or dermatomyositis. The goal of this research study is to better understand the environmental risk factors that may result in these diseases.

Girls seem to be going through puberty a lot earlier these days and doctors think it may be related to body weight. This study researches whether overweight girls go through puberty earlier than normal weight girls.

This study evaluates subjects with adult- and childhood-onset myositis to learn more about their causes, and the immune system changes and medical problems associated with them.

Childhood central nervous system (CNS) germ cell tumors form from germ cells (a type of cell that forms as a fetus develops and later becomes sperm in the testicles or eggs in the ovaries). Learn about the signs, tests to diagnose, and treatment of pediatric germ cell tumors in the brain in this expert-reviewed summary.

Childhood hematopoietic cell transplantation involves the infusion of blood stem cells into a patient to reconstitute the blood system. Get detailed information about autologous and allogeneic transplant, HLA matching, preparative regimens, and complications in this summary for clinicians.

Treatment for children with central nervous system germ cell tumors (GCT) depend upon the specific tumor type. Options include radiation therapy, chemotherapy, surgery (in various combinations) and stem cell rescue. Get detailed information about GCTs in this clinician summary.

Treatment options for children with astrocytomas include observation, surgery, chemotherapy, radiation therapy, and targeted therapy. Get detailed information about the treatment of newly diagnosed and recurrent childhood astrocytomas in this summary for clinicians.

Treatment options for children with craniopharyngioma include surgery, radiation therapy, cyst drainage, intracavitary instillation therapy, and immunotherapy. Get detailed information about treatment of newly diagnosed and recurrent childhood craniopharyngioma in this summary for clinicians.

Central nervous system atypical teratoid/rhabdoid tumor (AT/RT) treatment in children includes surgery, chemotherapy, and radiation therapy. A standard treatment has not been determined. Get detailed information for newly diagnosed and recurrent childhood AT/RT in this summary for clinicians.

Childhood central nervous system atypical teratoid/rhabdoid tumor treatment may include surgery, radiation therapy, chemotherapy, and high-dose chemotherapy with stem cell rescue. Learn more about newly diagnosed and recurrent childhood AT/RT in this expert-reviewed summary.