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In 2012, approximately 21,000 passenger vehicle occupants died in motor vehicle crashes in the United States; 52% were unrestrained at the time of the crash (1). An additional estimated 2.6 million nonfatal injuries from motor vehicle crashes were treated in emergency departments (2).

The documents Preexposure Prophylaxis for the Prevention of HIV Infection — 2014: a PHS Clinical Practice Guideline* and a Clinical Providers' Supplement† are now available online.

Khat (Catha edulis) is widely used in East Africa and the Middle East, often in combination with tobacco smoking. Sleep disturbance has been linked with habitual khat use; however, no systematic attempt has been made to test the hypothesis that use of khat and khat and tobacco in combination are related to sleep disturbance. Sleep disturbances are associated with dysregulations in emotional and physiological functions and can increase health risks.

The global tobacco epidemic contributed to 100 million deaths worldwide during the 20th century and continues to kill nearly 6 million persons each year, including approximately 600,000 from secondhand smoke. If current trends persist, an estimated 500 million persons alive today will die from the use of tobacco products. By 2030, tobacco use will result in approximately 8 million deaths worldwide each year.

Edna K. Moturi, MBChB1, Kimberly A. Porter, PhD2, Steven G.

Marc Fischer, MD1, J. Erin Staples, MD1 (Author affiliations at end of text).

Aron J. Hall, DVM1, Mary E. Wikswo, MPH1, Kimberly Pringle, MD2, L.

Water is the foundation for life. Learn more about the vital role safe water plays in our lives and what CDC is doing to address challenges to our water supply.

CDC Centers for Disease Control and Prevention Influenza Flu - findings from the Internet Panel Survey of pregnant women flu vaccination in the United States for the 2010-11, 2011-12, and 2012-13 flu seasons.

CDC works to identify causes of birth defects and opportunities to prevent them. By applying a public health approach incorporating three essential elements—surveillance or disease tracking, research to identify causes, and prevention research and programs—we can rapidly translate scientific findings into appropriate public health interventions.