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Do you tend to look on the sunny side, or do you see a future filled with dark, stormy skies? A growing body of research suggests that having a positive outlook can benefit your physical health. NIH-funded scientists are working to better understand the links between your attitude and your body. They’re finding some evidence that emotional wellness can be improved by developing certain skills.

For those who dream of being parents, pregnancy problems can be tremendously frustrating and disappointing. In recent decades, scientists have developed a wide range of approaches to help struggling couples have healthy babies. And NIH-funded studies are continuing to search for even better ways to overcome the challenges of infertility.

As you age, you may notice you have less muscle and energy and more fat. Carrying those extra pounds may be harming your health. It’s easy to be confused by advice about diet and exercise, but they’re key to avoiding weight gain as you get older.

The majority of competing applications now require electronic application submission. The Funding Opportunity Announcement (FOA) to which you are applying will identify whether you must submit electronically or use paper submission. Note that paper submissions require use of the PHS 398 application form, while electronic submission requires the SF424 (R&R) application.

Around the Nation and Worldwide NIH conducts clinical research trials for many diseases and conditions, including cancer, Alzheimer’s disease, allergy and infectious diseases, and neurological disorders. To search for other diseases and conditions, you can visit ClinicalTrials.gov.

NOMID, or neonatal-onset multisystem inflammatory disease, is a rare disease that is often fatal. This video tells the story of Kayla Martínez, who was diagnosed with NOMID as a baby. It also tells the story of a treatment for NOMID that was discovered by Dr. Raphaela Goldbach-Mansky at the National Institute of Arthritis and Musculoskeletal and Skin Diseases at the National Institutes of Health.

List of Registries Personal Stories For Parents and Children For Health Care Providers Resources for Trial Sites Educational Resources Glossary of Common Terms If You Have a Question In the News Taking a swing at Alzheimer’s disease Ollie Doolittle helps researchers learn more about the aging brain Ollie and Vernie Doolittle with their arms around each other. Ollie and Vernie Doolittle. 81-year-old Ollie still plays on three softball teams.(Photo credit: UC Davis Alzheimer’s Center) The bond between Ollie and Vernie Doolittle has endured though 60 years of marriage and military service during two wars. They still never go to bed angry (most of the time).

Personal Clinical Research Trials Personal Stories Volunteer and Researchers

Children are not little adults, yet they are often given medicines and treatments that were only tested in adults. There is a lot of evidence that children’s developing brains and bodies can respond to medicines and treatments differently than how adults respond. The way to get the best treatments for children is through research designed specifically for them.